In recent years, with the rapid development of syringe […]
In recent years, with the rapid development of syringe drug packaging technology at home and abroad, many pharmaceutical manufacturers have affected the compression rate of the rubber stopper after filling the syringe drug packaging and whether the rubber stopper produces particles and the amount of air remaining in the syringe. The size is gradually valued. This requires systematic consideration of the diameter of the rubber stopper guide tube, the smoothness of the inner wall and the characteristics of the medicine.
At present, there are two main problems with the rubber stopper guide tube for syringe drug packaging:
1. The gap between the outer wall of the rubber stopper guide cylinder and the inner wall of the syringe and the smoothness and compression rate of the rubber stopper and the inner wall of the rubber stopper guide cylinder during operation. The smoothness of the inner wall of the rubber stopper guide tube is too low and the friction coefficient is too large, which will easily produce particles on the rubber stopper; the inner diameter of the rubber stopper guide tube is too small to affect the compression rate of the rubber stopper, and the compression rate is too large, which not only destroys the characteristics of the rubber stopper , It will also increase the friction coefficient of the inner wall and cause the production of rubber plug particles.
2. For anaerobic drugs, the inert gas must be filled with nitrogen before the plugging. In this way, it must be considered that the rubber plug will pass through the rubber plug guide tube due to the nitrogen hole due to the existence of the nitrogen hole when the rubber plug enters. Particles are generated by scratching, so it is necessary to consider how to arrange the nitrogen holes scientifically and reasonably and define the size of the inner diameter of the nitrogen holes.
Syringe drug packaging materials mainly include glass prefilled syringes and plastic prefilled syringes, with or without needles, as well as syringes with needles. According to the application objects, there are two main types of syringes: human syringes and veterinary syringes.
Human syringes are generally mainly used for surgical irrigation, or pre-filling of some first-aid drugs for use. The syringes can effectively improve the efficiency of syringe use, effectively ensure the accuracy of medication, and avoid waste of drugs.
The veterinary syringe packaging is mainly used for feeding pet nutrition cream and pet medicine, such as cat and dog nutrition cream, generally 20ml, 30ml and 60ml products are used. The syringe pet medicine package can be used as both a package and a syringe. The operation is simple and easy to use.