Nowadays, with the continuous development of the pharma […]
Nowadays, with the continuous development of the pharmaceutical industry, the syringe medical packaging has undergone continuous improvement. The original glass material is replaced by a more excellent plastic material. The syringe medical packaging has a simple structure, mainly composed of tube sleeves, push rods, and protective caps. , The piston is composed, and the push rod can be printed with scales, which can effectively ensure the accuracy of medication.
The medical packaging of the syringe is full-filled, and the solution in the syringe cannot be shaken in the syringe, nor can it form a vortex. Therefore, when the syringe medical packaging is undergoing light inspection, it cannot be shaken and turned upside down as in the case of the vial light inspection, so as to inspect the visible foreign body under the light of the light inspection instrument. Moreover, because the needle tube is slender, it is difficult to find small deviations in volume. Only when comparing under the same conditions, it is easier to find a small amount of solution volume deviation.
The existing method of light inspection for medical packaging of syringes is to manually take out the syringes from the nest box one by one. After the light inspection for visible foreign body inspection is completed, it needs to be placed horizontally on the table to compare the volume of the solution. Put it back in the nest box.
When producing medical packaging syringes, it is impossible to be bubble-free, and some air molecules will still remain in the syringe even under the lowest vacuum. If the best process conditions are used, the bubbles may be so small that they are invisible to the naked eye. The size of the remaining bubbles mainly depends on the vacuum in the syringe and the filling level during operation. The amount of dissolved gas is negligible. For example, the traditional vacuum stopper method is used: Fill a 1ml (long) syringe with 0.75ml of water-based product and press the stopper at a pressure of 100mbar to produce a diameter of 2mm bubble (based on 1000mbar pressure).
As the gas is dissolved in the product, the volume of bubbles can be reduced by about 10%. Generally speaking, the pressure in the medical packaging syringe must be significantly higher than the vapor pressure of the product. Low vacuum, low friction, high filling level, high gas solubility, and the use of push rods will reduce the residual gas space in the syringe.